ABCB1 and ABCC1 single-nucleotide polymorphisms in patients treated with clozapine
نویسندگان
چکیده
منابع مشابه
ABCB1 and ABCC1 single-nucleotide polymorphisms in patients treated with clozapine
Clozapine (CZ) has superior efficacy to other antipsychotic agents in the treatment of schizophrenia and has been extensively used in clinical practice. ATP-binding cassette (ABC) transporter proteins are responsible for the distribution of various molecules as well as drugs across extracellular and intracellular membranes, including the blood-brain barrier. Genetic variations in these proteins...
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ژورنال
عنوان ژورنال: Pharmacogenomics and Personalized Medicine
سال: 2017
ISSN: 1178-7066
DOI: 10.2147/pgpm.s142314